<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0"><channel><title><![CDATA[RP Hope]]></title><description><![CDATA[Nonprofit supporting families affected by non-syndromic retinitis pigmentosa.]]></description><link>https://www.rphope-events.org/rp-posts</link><generator>RSS for Node</generator><lastBuildDate>Sun, 08 Nov 2026 19:14:41 GMT</lastBuildDate><atom:link href="https://www.rphope-events.org/blog-feed.xml" rel="self" type="application/rss+xml"/><item><title><![CDATA[Annual Tax Filings]]></title><description><![CDATA[Annual tax filings]]></description><link>https://www.rphope-events.org/post/990-ez-2021</link><guid isPermaLink="false">681ae56485ea23f277f4eb9f</guid><category><![CDATA[Admin]]></category><pubDate>Wed, 07 May 2025 04:45:29 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/11062b_69f7760c31724b2eb990506a9c18967e~mv2.jpg/v1/fit/w_1000,h_951,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Carin Elam</dc:creator></item><item><title><![CDATA[CRX retinopathy project]]></title><description><![CDATA[Dr. Shiming Chen (Opthalmology &#38; Visual Sciences  – Washington University) has an exciting new study  and  is recruiting CRX families.]]></description><link>https://www.rphope-events.org/post/crx-retinopathy-project</link><guid isPermaLink="false">6799bf00ea6adb02fb6c86ab</guid><category><![CDATA[CRX]]></category><category><![CDATA[LCA]]></category><pubDate>Wed, 29 Jan 2025 05:48:27 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_2b86314f0eef40bc8c322fba33c0252d~mv2.jpg/v1/fit/w_1000,h_896,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Press Release</dc:creator></item><item><title><![CDATA[Clinical Characterization of CNGB1-Related Autosomal Recessive Retinitis Pigmentosa]]></title><description><![CDATA[To describe the detailed clinical and molecular genetic findings in a series of patients with RP with likely pathogenic variants in CNGB1.]]></description><link>https://www.rphope-events.org/post/clinical-characterization-of-cngb1-related-autosomal-recessive-retinitis-pigmentosa</link><guid isPermaLink="false">67986b569981b29b2939f019</guid><category><![CDATA[CNGB1]]></category><pubDate>Tue, 28 Jan 2025 05:42:29 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_88b03784eb2b4a89b3e874451053aa9d~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Hormones and protein development in females]]></title><description><![CDATA[Hormones significantly influence protein development particularly during menstruation and menopause, where  fluctuations in hormone levels  ]]></description><link>https://www.rphope-events.org/post/hormones-and-protein-development-in-females</link><guid isPermaLink="false">67570a2840c39754f4778dac</guid><category><![CDATA[Learn About RP]]></category><pubDate>Mon, 09 Dec 2024 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_4420759d00664871bab5683655079866~mv2.jpeg/v1/fit/w_664,h_443,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>AI Summary</dc:creator></item><item><title><![CDATA[Multigenerational Autosomal Recessive Best Disease]]></title><description><![CDATA[Retinal findings raised suspicion for this inherited retinal disease, confirmed with genetic testing.]]></description><link>https://www.rphope-events.org/post/multigenerational-autosomal-recessive-best-disease</link><guid isPermaLink="false">679d9815ce173527580a8387</guid><category><![CDATA[BEST1]]></category><category><![CDATA[Potential Treatments]]></category><pubDate>Sat, 30 Nov 2024 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_83eae355d02347d4be646d8571a2573e~mv2.png/v1/fit/w_1000,h_696,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[New Gene Therapy for Retinitis Pigmentosa Shows Promise]]></title><description><![CDATA[ New research . . . suggests that a new kind of gene therapy can improve vision in people who have lost nearly all sight to RP.]]></description><link>https://www.rphope-events.org/post/new-gene-therapy-for-retinitis-pigmentosa-shows-promise</link><guid isPermaLink="false">671d32aa231ba04d635d792c</guid><category><![CDATA[Potential Treatments]]></category><pubDate>Sun, 20 Oct 2024 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/nsplsh_675ad0429fdd419694dc026edb18331a~mv2.jpg/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Press Release</dc:creator></item><item><title><![CDATA[WHEN RARE IS RELATIVE]]></title><description><![CDATA[Although the IRD patient population is small compared with other retinal conditions, the research on novel therapeutic approaches is not. ]]></description><link>https://www.rphope-events.org/post/when-rare-is-relative</link><guid isPermaLink="false">679d9de8ce173527580a939b</guid><category><![CDATA[RPE65]]></category><category><![CDATA[LCA]]></category><category><![CDATA[Clinical Trial]]></category><pubDate>Wed, 31 Jul 2024 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_de986247845e4788ba85175fe4de5fd4~mv2.png/v1/fit/w_276,h_183,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Unraveling the CLCC1 interactome: Impact of the Asp25Glu variant and its interaction with SigmaR1 at the Mitochondrial-Associated ER Membrane (MAM)]]></title><description><![CDATA[The study illuminates the impact of the RP-associated Asp25Glu variant on CLCC1, showcasing a notable shift in its interaction profile.]]></description><link>https://www.rphope-events.org/post/unraveling-the-clcc1-interactome-impact-of-the-asp25glu-variant-and-its-interaction-with-sigmar1-at</link><guid isPermaLink="false">67970af466e76ecb19f12148</guid><category><![CDATA[CLCC1]]></category><pubDate>Fri, 31 May 2024 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_3d41eb834e784c2b9a969e305f1d13d4~mv2.png/v1/fit/w_145,h_160,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial]]></title><description><![CDATA[Here, we report results of the first-in-human clinical trial (NCT04722107) of gene therapy for Bietti crystalline corneoretinal dystrophy]]></description><link>https://www.rphope-events.org/post/gene-replacement-therapy-in-bietti-crystalline-corneoretinal-dystrophy-an-open-label-single-arm-e</link><guid isPermaLink="false">679e4bf98f4af8f9ed168d4a</guid><category><![CDATA[CYP4V2]]></category><category><![CDATA[RPE65]]></category><category><![CDATA[Clinical Trial]]></category><pubDate>Wed, 24 Apr 2024 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_90e4c8bbe20d4d74bf52741c67cc86fa~mv2.jpg/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Academic Paper</dc:creator></item><item><title><![CDATA[Progression of PROM1-Associated Retinal Degeneration as Determined by Spectral-Domain Optical Coherence Tomography Over a 24-Month Period]]></title><description><![CDATA[Significant thickness losses could be detected in outer retinal layers by SD-OCT over a 24-month period in patients with PROM1-associated RD]]></description><link>https://www.rphope-events.org/post/progression-of-prom1-associated-retinal-degeneration-as-determined-by-spectral-domain-optical-cohere</link><guid isPermaLink="false">6049246edf354300584ff5d0</guid><category><![CDATA[LCA]]></category><category><![CDATA[PROM1]]></category><category><![CDATA[Potential Treatments]]></category><pubDate>Sat, 30 Mar 2024 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_3d41eb834e784c2b9a969e305f1d13d4~mv2.png/v1/fit/w_145,h_160,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Gene Therapy Improves Functional Measures in XLRP]]></title><description><![CDATA[Patients with XLRP treated with AGTC-501 gene therapy experienced improvements in visual function including retinal sensitivity  . . . ]]></description><link>https://www.rphope-events.org/post/gene-therapy-improves-functional-measures-in-xlrp</link><guid isPermaLink="false">66fa0c31412de08579931eac</guid><category><![CDATA[Potential Treatments]]></category><category><![CDATA[RPGR]]></category><pubDate>Thu, 14 Mar 2024 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_a9411a3407e04337bf86081dca9cbca8~mv2.jpg/v1/fit/w_753,h_696,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[A Systematic Literature Review of Disease Progression Reported in RPGR-associated X-Linked Retinitis Pigmentosa]]></title><description><![CDATA[A systematic literature review was conducted to assess available data on disease progression in RPGR-associated XLRP.]]></description><link>https://www.rphope-events.org/post/a-systematic-literature-review-of-disease-progression-reported-in-rpgr-associated-x-linked-retinitis</link><guid isPermaLink="false">66fa111bdb76332839ce54b4</guid><category><![CDATA[RPGR]]></category><pubDate>Wed, 31 Jan 2024 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_0d66719e5f4d43a5a5df40a316c68be9~mv2.png/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Preclinical dose response study shows NR2E3 can attenuate retinal degeneration in the retinitis pigmentosa mouse model RhoP23H+/−]]></title><description><![CDATA[Study demonstrates effectiveness of different doses of NR2E3 at reducing retinal degeneration and informs dose selection for clinical trials]]></description><link>https://www.rphope-events.org/post/preclinical-dose-response-study-shows-nr2e3-can-attenuate-retinal-degeneration-in-the-retinitis-pigm</link><guid isPermaLink="false">67a457955f6fb95ab00d0a26</guid><category><![CDATA[NR2E3]]></category><category><![CDATA[RHO]]></category><category><![CDATA[RPE65]]></category><pubDate>Fri, 26 Jan 2024 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_971c8d2218624ae29ceec4caba3b5941~mv2.png/v1/fit/w_1000,h_877,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Academic Paper</dc:creator></item><item><title><![CDATA[Liquid-metal-based three-dimensional microelectrode arrays integrated with implantable ultrathin retinal prosthesis for vision restoration]]></title><description><![CDATA[Presents a soft artificial retina where flexible ultrathin photosensitive transistors are integrated with three-dimensional stimulation . . ]]></description><link>https://www.rphope-events.org/post/liquid-metal-based-three-dimensional-microelectrode-arrays-integrated-with-implantable-ultrathin-ret</link><guid isPermaLink="false">67cd0b48b1797c58cdaf767d</guid><category><![CDATA[Potential Treatments]]></category><pubDate>Mon, 15 Jan 2024 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_40831dda7be8478692e8013f682d2c29~mv2.jpg/v1/fit/w_1000,h_646,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Academic Paper</dc:creator></item><item><title><![CDATA[Retinitis pigmentosa with or without skeletal abnormalities due to homozygous mutations in the CWC27 gene: A case report]]></title><description><![CDATA[Study adds to our understanding of the clinical phenotype of TBL1XR1 mutations and provides a realistic and reliable basis for clinicians.]]></description><link>https://www.rphope-events.org/post/retinitis-pigmentosa-with-or-without-skeletal-abnormalities-due-to-homozygous-mutations-in-the-cwc27</link><guid isPermaLink="false">679aee28a76d543a313bf22f</guid><category><![CDATA[CWC27]]></category><pubDate>Fri, 22 Dec 2023 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_d82dc452dd8946aead4ac75385b9474c~mv2.jpeg/v1/fit/w_460,h_392,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Mutations in AGBL5 associated with Retinitis pigmentosa]]></title><description><![CDATA[Diego I. Paredes, Nicholas R. Bello, Jenina E. Capasso, Rebecca Procopio, Alex V. Levin | Ophthalmic Genetics | 45(3) | 275-280 |...]]></description><link>https://www.rphope-events.org/post/mutations-in-agbl5-associated-with-retinitis-pigmentosa</link><guid isPermaLink="false">66f947a0db76332839cbd06f</guid><category><![CDATA[AGBL5]]></category><pubDate>Mon, 11 Dec 2023 14:19:23 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_6dd27f1f91f64507beec7c038488ae0b~mv2.jpg/v1/fit/w_750,h_350,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Rare IFT140-Associated Phenotype of Cranioectodermal Dysplasia and Features of Diagnostic Journey in Patients with Suspected Ciliopathies]]></title><description><![CDATA[Biallelic pathogenic variants in IFT140 or other IFT-A complex genes can cause defective retrograde cilial transport. ]]></description><link>https://www.rphope-events.org/post/rare-ift140-associated-phenotype-of-cranioectodermal-dysplasia-and-features-of-diagnostic-journey-in</link><guid isPermaLink="false">671acde951817f0606e8108e</guid><category><![CDATA[IFT140]]></category><pubDate>Tue, 20 Jun 2023 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_b2487e7135fd4888a305a93885e627a7~mv2.png/v1/fit/w_225,h_225,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[Overcoming the Challenges to Clinical Development of X-Linked Retinitis Pigmentosa Therapies: Proceedings of an Expert Panel]]></title><description><![CDATA[Formulate recommendations for designing XLRP gene therapy clinical studies to provide the best chance of successful treatment development.]]></description><link>https://www.rphope-events.org/post/overcoming-the-challenges-to-clinical-development-of-x-linked-retinitis-pigmentosa-therapies-procee</link><guid isPermaLink="false">66f9ec10f6e41b36dcd4dffc</guid><category><![CDATA[RPGR]]></category><category><![CDATA[RP2]]></category><category><![CDATA[Forms of RP]]></category><pubDate>Fri, 09 Jun 2023 07:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/nsplsh_6a7851464d4e37787a4a63~mv2_d_4794_2697_s_4_2.jpg/v1/fit/w_1000,h_1000,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Journal Article</dc:creator></item><item><title><![CDATA[USHER SYNDROME COALITION]]></title><description><![CDATA[Usher Syndrome Coalition’s mission raise awareness and accelerate research for most common genetic cause of combined deafness  and blindness]]></description><link>https://www.rphope-events.org/post/usher-syndrome-coalition</link><guid isPermaLink="false">63edab4a04b895319c0b62d5</guid><category><![CDATA[USH2A]]></category><category><![CDATA[USH3A]]></category><category><![CDATA[CLRN1]]></category><pubDate>Wed, 01 Feb 2023 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_1692da8553034a27ab45cd3829712411~mv2.png/v1/fit/w_500,h_500,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Carin Elam</dc:creator></item><item><title><![CDATA[PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing]]></title><description><![CDATA[PRPF8 mutations have been associated with severe forms of RP and with the initiation of various types of myeloid neoplasms . . .]]></description><link>https://www.rphope-events.org/post/prpf8-increases-the-aggressiveness-of-hepatocellular-carcinoma-by-regulating-fak-akt-pathway-via-fib</link><guid isPermaLink="false">671a5b0dfd623d5be608ecb8</guid><category><![CDATA[PRPF8]]></category><category><![CDATA[Forms of RP]]></category><pubDate>Fri, 06 Jan 2023 08:00:00 GMT</pubDate><enclosure url="https://static.wixstatic.com/media/77bbd3_c9ce91595d6144bf887cf75f1a017bd7~mv2.jpg/v1/fit/w_800,h_450,al_c,q_80/file.png" length="0" type="image/png"/><dc:creator>Academic Paper</dc:creator></item></channel></rss>